Guide
A CISO's Guide to Stopping Human and AI-centric Threats
This Proofpoint guide examines how organizations can defend against increasingly sophisticated human- and AI-driven cyber threats, including phishing, ransomware, business email compromise (BEC), account takeovers, data loss, and prompt injection attacks targeting AI assistants. The report notes a 94% increase in email threats in 2025 and highlights how attackers are using AI to automate campaigns, personalize phishing attempts, and scale social engineering attacks. To address these risks, organizations should focus on five key capabilities: comprehensive threat visibility, AI-powered threat detection and protection, security for trusted business communications, employee risk awareness and training, and account takeover protection. The guide emphasizes that effective defense requires an integrated security platform combining threat intelligence, behavioral analytics, machine learning, and user education rather than relying on fragmented point solutions.
