This report maps major population-scale genomics initiatives worldwide, examining their objectives, governance models, funding mechanisms, and data-sharing approaches. It highlights how countries are investing in genomics to advance precision medicine, improve disease prevention, and strengthen research ecosystems. The analysis compares national programs across Europe, Asia, and the Americas, noting differences in scale, ethical frameworks, and integration into healthcare systems. Key challenges include data privacy, interoperability, workforce readiness, and equitable access. The report concludes that coordinated policy, public trust, and sustainable infrastructure are critical to translating genomic data into real-world health benefits.

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