The Use Software to Tackle the Science Replication Problem infosheet addresses the growing challenge of reproducibility in scientific research. A significant portion of research spending is lost each year because studies cannot be successfully replicated, raising concerns about the reliability of scientific findings. As data volumes increase and research becomes more complex, scientists often struggle to reproduce results even when working with the same datasets. The report highlights how inconsistent data management, poor documentation, fragmented workflows, and lack of traceability contribute to this problem. It advocates for the use of digital and cloud-based scientific software to standardize processes, improve data capture, and ensure experimental information is accurately recorded an

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