This white paper analyzes global drug shortage trends, their root causes, and their impact on healthcare systems. It examines manufacturing concentration, API sourcing, regulatory delays, and geopolitical risks contributing to supply vulnerability. Using recent shortage data, the report highlights economic, clinical, and humanistic consequences of medicine scarcity. It outlines mitigation strategies including supply diversification, advanced monitoring, and policy coordination. The paper concludes that resilient, data-driven supply chains are essential to ensuring sustained access to essential medicines worldwide.

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