This white paper presents practical guidance on avoiding failure in AI initiatives, based on real-world experience from hundreds of projects in chemical and materials companies. It highlights that while only about 15% of AI projects succeed industry-wide, most Citrine Informatics customers generate value within the first year. Key lessons include educating teams, creating a shared vision, choosing the right AI partner, and selecting initial projects strategically. The paper stresses starting with minimal data, tracking progress, and scaling deliberately. Equal emphasis is placed on people and culture, celebrating successes, and overcoming resistance such as the “not invented here” mindset to ensure long-term AI impact.

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